CATALYTIC
REACTIONS |
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In
response to the Call
for Catalytic Reactions, I would like to register the following:
On
Research Challenges
One of the
key challenges in responding to many of the scientific issues we
need to address is the paucity of clinical research staff both on
campus, as well as extramurally on the domestic and global scenes
(particularly in countries where some of the most urgent disease
problems exist). In order to move the burgeoning basic research
findings through translational and then clinical and population-based
studies, the research personnel issues must be addressed. Doubling
the NIH research budget without doubling and tripling the budget
for research training and career development may be the most important
challenge facing us.
On
Special Interest Group (SIG) Effectiveness
Perhaps the
SIGs have reports and recommendations that might be disseminated
broadly, not only to IC Scientific Directors but to IC Directors
and their planning offices as well as to program directors administering
both intramural and extramural portfolios.
On
Catalyst Coverage
It might be
edifying to learn about international collaborations that evolve
from initial collaborative research projects between and among intramural
scientists and Visiting Scientists. Once foreign scientists return
to their home countries, are there continuing collaborations and
are there new collaborations that evolve with our extramural scientist
communities? These case studies might be useful not only in justifying
the various programs but in stimulating additional needed international
collaborative research.
Lois
K. Cohen, Director,
NIDCR
Office of International Health
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Regarding
extramural funding for clinical research training, NIH launched three
award programs in fiscal 1999:
The Clinical Research Curriculum Award (K30) enables institutions
to provide didactic training on the fundamentals of conducting clinical
research. Courses may include, but are not limited to, study design,
biostatistics, bioethics, and regulatory issues.
The Mentored Patient-Oriented Career Development Award (K23) enables
individuals to obtain mentored research experience.
The Mid-Career Investigator in Patient-Oriented Research Award (K24)
is a complement to K23, providing support to the mentors and allowing
them protected time to devote to patient-oriented research.
Since
their inception, NIH has funded a cumulative total of 496 K23 awards
and 215 K24 awards; 57 K30 awards were made in FY 2001.
An
additional NCRR-funded clinical career development award to help
institutions develop degree-granting programs in clinical research
was launched in FY 2002. It is anticipated that 10 programs will
be funded during the pilot phase.
Belinda
Seto, OER
Regarding
the next chapter in the research lives of visiting scientists once
they go back home, see "GRIP Strength:
Building Bridges to Developing Countries One Scientist at a Time"
on a related NIH programEd
On
Important Questions in
Biomedical Research Today
What is the
earth's sustainable population and how can we humanely reduce our
population to that level?
Carl
Henn, OD
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BEHAVIORAL
AND SOCIAL SCIENCES
RESOURCES AT THE NIH LIBRARY
The
NIH Library offers access to key resources relevant to the behavioral
and social sciencesmany available via a desktop computer from
the Librarys web page.
Below is a
guide to some of the more important resources. (The Library also
conducts training classes, personal tutorials, and online animated
tutorials in effective search techniques; click on "Training"
at the Librarys website.)
For books, search the NIH Library catalog
or Books-In-Print.
Items
in Books-In-Print can be ordered.
Journals can also be found in the catalog, and a list of
online journals can be accessed from the Librarys web
page under "Electronic Resources, Online Journals." Additional
online journals are available from ScienceDirect and JSTOR, a digital
archive of back issues of more than 100 journals in the arts and
sciences, including many sociological and anthropological titles.
The Library provides desktop access to databases covering
the behavioral and social sciences literature. These resources,
featured below, can be accessed from the Librarys web page
under "Electronic Resources, Databases." (Librarians can
also search these and other databases, such as Sociological Abstracts.
To arrange this, call 496-1080 (MondayFriday, 8:30 a.m5:00
p.m.).
HAPI
(Health and
Psychosocial Instruments) provides
information on measurement instruments in the health fields, psychosocial
sciences, and organizational behavior and identifies measures needed
for research studies, grant proposals, client/patient assessment,
and program evaluation.
PsycINFO
covers
the professional and academic literature in psychology and related
disciplines, indexing more than 1,300 journals from 1887 on. The
alert service provides e-mail updates.
WEB
OF SCIENCE allows
searching the Social Sciences Citation Index, which contains bibliographic
information and cited references from more than 1,700 social sciences
journals from 1980 on. The Porpoise alert service provides weekly
e-mail updates.
MATHSCINET
provides access
to Mathematical Reviews and Current Mathematical Publications from
1940 on. Bibliographic data and review texts are available from
1975 on.
The Library
also provides Customized Library Services for a fee to groups
needing assistance with large projects. Librarians can develop search
strategies, conduct online database searches, and develop databases
using bibliographic software such as EndNote or Reference Manager.
For more info on custom services, call Susan
Whitmore at 301-496-1157.
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HISPANIC
HERITAGE MONTH CELEBRATION:
TWO PARTS
"Language
and Access to Care" is the theme of the 2002 NIH Hispanic Heritage
Month Celebration, Part 1, taking place Thursday, September
19, 9:00 a.m.12:30 p.m.,
in Lipsett Auditorium, Building 10.
Remarks by
Marta
Leon-Monzon, president of the NIH Hispanic Employee Organization,
NIH Director Elias
Zerhouni, and US Surgeon General Richard Carmona will precede
lectures by Thomas Münte on "How to Handle Two Languages
with One Brain: A Neuroscience Perspective," Nilda Peragallo
on "Language and Culture: Bridges or Barriers," and Carlos
Zarate on "Pilot Hispanic Research Initiative in Mood Disorder
Patients."
An exhibit
and reception follow at the Building 10 Visitor Information Center,
12:302:00 p.m.
Part 2NIH
Hispanic Scientists Daywill be held at Lipsett Thursday,
October 10, 12 noon3:00 p.m.
It kicks off with a talk by Antonio Fojo on "Multidrug Resistance
in Cancer: Laboratory Studies and Clinical Correlates," followed
by a talk on NIH grant opportunities and positions by Milton
Hernandez. and concludes with posters and a reception at the
Visitor Center. For more info, contact Leon-Monzon
at 496-4564.
Sign language
interpretation will be provided. For reasonable accommodations to
participate in this event please contact the NIH Office
of Equal Opportunity and Diversity Management at 301-496-6301.
Additional information is available at this website.
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CSR
SEEKS INTERNS
The
Center for Scientific Review
(CSR) is seeking new recruits for its Review Internship
Program, which offers scientists training and experience in
scientific research administration. Interns will work with a diverse
and dedicated group of scientists in their fields and help coordinate
state-of-the-art scientific review meetings. This year, CSR is encouraging
NIH intramural scientists as well as those in academia and industry
to apply.
Applications
submitted by November 1, 2002,
will be considered for positions starting no sooner than February
2003. Applications submitted by February 1, 2003, will be considered
for positions starting in August 2003.
Additional
information about the program, application forms, and other requirements
can be found on the CSR website.
General inquiries
about this new program can be directed to Mary
Elizabeth Mason at 301-435-1114.
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SALZMAN
AWARD
The
Foundation for the NIH and the
NIH Virology Interest Group
announce the Fourth Annual Norman P. Salzman Memorial Award in Virology.
This award has been established to recognize an outstanding research
accomplishment by a postdoctoral fellow or research trainee working
in the field of virology at NIH. The award honors Salzmans
40-year career in virology research and his accomplishments in mentoring
young scientists. The winning fellow will receive a plaque and an
unrestricted gift of $2,500; the mentor will receive a plaque. Information
about the award and the Norman P. Salzman symposium to be held at
NIH on November 7th can be found
at the interest group website.
Application
deadline for the award is September 21,
2002.
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GENETICALLY
MODIFIED MOUSE
STRAINS AVAILABLE
The
network of Mutant Mouse
Regional Resource Centers (MMRRC), established to accept mutant
mice from donating investigators for the purpose of transferring
the strains to requesting investigators or institutions, now has
six available strains. These genetically modified strains
include models for studies of cardiovascular disease, cancer, diabetes,
obesity, and epilepsy. Strains are supplied either from a production
colony or from a colony recovered from cryopreservation.
Details of
available strains as well as a list of new strains
currently under development can be found at the MMRRC website,
where investigators may now register their interest in new strains.
The site includes
information on distribution policies and fees. Fees are intended
to defray the costs of specialized mouse breeding, genetic quality
control, animal health monitoring, and cryopreservation. Material
Transfer Agreements, also reviewed at the website, are required
to ensure fair and reasonable balance for donors and recipients
in the sharing of these mouse strains among researchers for internal
noncommercial research.
The MMRRC
network is supported by NCRR and currently includes four repository-distribution
facilities located at the University of North Carolina at Chapel
Hill, the University of California at Davis, Taconic Farms in New
York, and Harlan Sprague Dawley, Inc., in collaboration with the
University of Missouri. Contact information for each MMRRC is available
at the NCRR website (linked
from "announcements").
Each MMRRC
facility is equipped to cryopreserve embryos or gametes, rederive
strains as needed, and characterize the genetic and phenotypic makeup
of the mutants so that models are validated and may optimally serve
as models of human disease.
Efficient
facility systems provide genetic quality control and disease safeguards.
The MMRRCs offer expertise in the biology of laboratory micecovering
areas of cryobiology, genetics, comparative pathology, behavioral
science, and infectious disease.
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GRAND
ROUNDS WITH GREAT
TEACHERS
The
20022003 series of NIH/CC Grand
Rounds in Contemporary Clinical Medicine opens September 18
and continues monthly through June12
noon to 1:00 p.m., Wednesdays, in the Lipsett Amphitheater,
Building 10.
September 18: Thyroid
Disease, Daniel Federman, Harvard Medical School, Boston
October 9: Developmental
Disabilities, Martha Bridge Denckla, Johns Hopkins University
School of Medicine, Baltimore
November 13: Arthritis,
Nathan Zvaifler, University of California, San Diego
December 11: Osteoporosis,
Clifford Rosen, Maine Center for Osteoporosis Research and Education,
Bangor
January 15: Pain,
Kathleen Foley, Memorial Sloan-Kettering Cancer Center, New York
February 12: Asthma,
Jeffrey Drazen, Harvard Medical School
March 12: Surgery
with Extracorporeal Membrane Oxygenation, Robert Bartlett,
University of Michigan Medical Center, Ann Arbor
April 9: Electrolyte
Disorders, Robert Narins, American Society of Nephrology
May 14: Depression,
Charles Nemeroff, Emory University School of Medicine, Atlanta
June 11: Thinking
about Infectious Disease, John
Bennett, NIAID
This CME series
carries a maximum of 48 hours in category 1 credit toward the AMA
Physician Recognition Award.
For reasonable
accommodations, call 496-2563 at least five business days in advance.
Lectures will be videocast.
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HONORED
MENTORS
Nominees
for the 2002 NIH Distinguished Clinical Teachers Award (DCTA)
will be honored at the Clinical
Center Grand Rounds, September 25,
12:001:00 p.m., in the Lipsett Auditorium. The
DCTA is the highest honor bestowed collectively by the NIH Clinical
Fellows on an NIH senior clinician, staff clinician, or tenure-track/tenured
clinical investigator for excellence in mentoring, teaching, and
research. Clinical Fellows from nine institutes nominated 14 individuals.
They are:
NCI: H.
Richard Alexander, Maria
Merino, Thomas
Walsh
NHLBI: John
Barrett, Cynthia
Dunbar
NIA: Josephine
M. Egan
NIAID: Steve
Holland
NIAMS: Gregory
Dennis
NICHD: Lynnette
Nieman, Owen
Rennert
NIDDK: Jay
Hoofnagle
NIMH: Trey
Sunderland
NINDS: Mark
Hallett, Barbara
Karp
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