A MAJOR FOCUS OF NEW
major research focus of Jacob Hochman of the Hebrew University of
Jerusalem has been xenogenization (a process by which tumor cells
are rendered immunogenic instead of tumorigenic), growth regulation,
and metastasis of malignant lymphoma. His unique mouse model of
these processes is the only one currently available that can also
be used for molecular analysis of the infiltration of lymphoma through
the blood-brain barrier into the brain and subsequent migration
along the optic nerve sheath into the eye.
collaborators over the years are NIH scientists who have pressed
for his nomination to be a Fogarty Scholar and with whom he will
be working during his Fogarty tenure here (divided over several
years; this year, from June to September).
Hanover, chief of the Laboratory
of Cell Biochemistry and Biology, NIDDK, Hochman plans to continue
studies on the role of nucleolar MMTV env-precursor proteins p14
and p21 in regulating tumorigenicity and immunogenicity of the experimental
lymphoma model as well as in other lymphomas harboring MMTV genes.
Gottesman, chief of the Laboratory
of Cell Biology, NCI, he plans to use MDR vectors for the selective
overexpression of p14 and p21 in recipient cells of differing backgrounds
and study their tumorigenic and immunogenic potential. The contribution,
direct or indirect, of the MDR P-glycoprotein to metastasis in the
lymphoma model to the brain and eyes will also be assessed.
Bustin, chief of the Protein Section, Laboratory
of Metabolism, NCI, he plans to study the possible interaction
of p14 and p21 with chromatin.
Wahl, chief of the Immunopathology
Section, NIDCR, Hochman has initiated study of the role of matrix
metalloproteinases in the metastasis of lymphoma cells into the
Collaborating with NEI investigators, he will investigate lymphoma
metastasis into and within the different compartments of the eye.
BENCH TO BUSINESS
program designed to introduce NIH scientists to entrepreneurship
in biotechnology and science will be held Thursday, April 18, from
1:00 to 5:15 p.m. in the Masur Auditorium. A reception will follow.
from the Bench into Business: Entrepreneurship in Science"
is aimed at anyone who has ever thought about starting a business
after leaving NIH or transferring their discoveries to others for
this purpose. The program will include:
The essential elements of a successful business plan
Presentations by entrepreneurs who transitioned from the bench to
Resources available to young companies
Insight into the differences in workplace cultures
The opportunity to network with interested colleagues and biotech
is free, but registration is requested at the website.
will also be webcast.
interpretation provided on requestcall Christy
Meek at (301) 451-6835. This program is sponsored by the Macklin
Business Institute Center for Entrepreneurship of Montgomery College,
NCI Office of Technology
and Industrial Relations, NCI Center
for Cancer Research, NCI Technology
Transfer Branch, NCI
Fellowship Office, NIH Office
of Education, NIH Foundation for
Advanced Education in the Sciences, and the NIH Graduate
Program Partnerships Office.
CREDIT AVAILABLE ONLINE
can now earn CME credits online, and at no cost, thanks to The
Oncologist CME Online service.
collection of CME-accredited courses focuses on cancer, as well
as risk management and supportive care. Physicians generally, and
oncologists specifically, who are interested in fulfilling state
board certification requirements without leaving their desks are
invited to explore this service. The Oncologist CME Online also
offers a portal to other online CME activities hosted by NIH.
user receives a unique online personal folder ("My CME")
that maintains a collection of completed CME courses as well as
access to printable certificates for completed courses. Completed
course credits are forwarded to the Accreditation Council for Continuing
Medical Education for official acceptance and are then available
to state board licensure agencies.
for Advanced Education in the Sciences designates this educational
activity for a period of 3 years in category 1 credit towards the
AMA Physicians Recognition Award.
for CME credit on or before December 31, 2002, will be recorded
in 2002. Courses submitted for CME credit on or after January 1,
2003, will be recorded in 2003.
For more information,
visit The Oncologist CME Online service website;
Foundation for the NIH and NCI will present the first annual Sallie
Rosen Kaplan Fellowship for Women Scientists in Cancer Research
Training Award (CRTA) on Thursday, April 4, 2002, at 4:00 p.m.
in the Natcher Building, Room A.
In this inaugural
year of the program, the award will be made to extend the fellowship
of a current postdoctoral CRTA recipient by one year. The intent
of the extension is to allow the recipient to continue productive
research that would otherwise be cut short were the fellowship appointment
to end as scheduled.
years, NCI will hold an annual, national competition through which
one or more starting CRTA postdocs will be honored as Sallie Rosen
TERM CARE ON MENU
care (LTC) insurance is now an option for federal employees. Coverage
includes but is not limited to care in a nursing home, assisted
living facility, home, or hospice, as well as respite care.
runs from March 25 to May 15, 2002. Regular open enrollment runs
from July 1 to Dec. 31, 2002.
A forum on
the federal LTC insurance program, held at Natcher March 6, was
videocast and can be viewed.
can be directed to institute and center human resources offices.
KNOW WHAT'S GOING
ON AT NIH . . .
. . . Click
onto the DDIRs Web Board. It comes out about once a
month with news about key intramural policy changes, fellowship
opportunities, tenure-track positions, interest group news, upcoming
lectures and workshops, electronic resources, and cool pix of intramural
To view the
newsletter, go to the sites new url.
send an e-mail message to this address.
your name for Jan Does, your message should say: Subscribe
DDIRBB-L Jan Doe. Alternatively, visit the ListServ website
for this Bulletin Board and
type in your name and e-mail address.